Home Invites Members Groups Events Careers Videos News Photos Blogs Polls Forums Chat
Home > Career Center > Job Seekers > Job Search
Job Title: Bioinformatics Scientist, Assay Development
Company Name: Guardant Health
Location: Palo Alto, CA United States
Position Type: Full Time
Post Date: 08/13/2022
Expire Date: 10/24/2022
Job Categories: Administrative and Support Services, Biotechnology and Pharmaceutical, Computers, Software, Education, Healthcare, Other, Healthcare, Practitioner and Technician, Information Technology, Manufacturing and Production, Other / General, Sales, Science, Research & Development, Medical
Job Description
Bioinformatics Scientist, Assay Development

Company Description

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has launched liquid biopsy-based Guardant360®, Guardant360 CDx and GuardantOMNI® tests for advanced stage cancer patients. These tests fuel development of its LUNAR program, which aims to address the needs of early stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection. 

Job Description

As a member of the Bioinformatics Laboratory Developed Test (LDT) Assay Development team, you will work closely with biologists across multiple development projects, supporting the development and deployment of our novel NGS assay. You will devise analytics to examine our experimental data, characterize assay attributes and finally improve the capability of our assay and bioinformatics pipelines. You will explore the unprecedented compendium of clinical data collected within Guardant Health, and collaborate with multiple function units, including the Software, Operations, Business Development and Medical Affairs.


  • Design and prototype computational methods to generate insights from experimental data for improving assays and bioinformatics pipelines
  • Formulate and conduct feasibility analysis to guide our new products, including statistical modeling or in-silico simulations drawing from a rich database of historical test results
  • Work in conjunction with assay development scientists to plan experiments in novel assay development, troubleshooting, and sustaining support of existing products
  • Precisely communicate analysis results to stakeholders across computational, experimental and business teams and proactively advocate for solutions based on the data insight


  • PhD in Bioinformatics, Biostatistics, Statistics, Computer Science, or related quantitative fields
  • Strong knowledge of statistics and computational biology algorithms for genomic analysis (including statistical methods employed in analytical validation) and cancer genomics (general multivariate statistical inference)
  • Demonstrated experience in developing analytical methods for experimental genomics data under the context of product development
  • Proficiency with a high-level scripting language (e.g. Python, R)
  • Excellent communication and teamwork skills to foster a highly collaborative environment, working with both experimental and computational scientists
  • Familiar with regulated development environments

Advantage if you have

  • 2+ years of relevant experience in Pharmaceutical or Biotech industry
  • Knowledge of cancer biology
  • Understanding of library preparation methods used to generate NGS data, including whole-genome and methylation sequencing, targeted sequencing, and RNA-seq

Additional Information

Hybrid Work Model: At Guardant Health, we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

Covid Vaccination Policy:  Starting January 7, 2022, Guardant Health will require all employees to be fully vaccinated to either (a) establish that they have been fully vaccinated against COVID-19; or (b) request and obtain an approved exemption from Guardant’s COVID-19 U.S. Vaccination Policy as a reasonable accommodation, as consistent with applicable laws.  An employee is considered fully vaccinated against COVID-19 two weeks after receiving the second dose of a two-dose vaccine or one dose of a single-dose vaccination. Acceptable vaccines are approved or under emergency use authorization by the U.S. Food and Drug Administration (FDA) and/or the World Health Organization (WHO). In addition, fully-vaccinated employees will be required to maintain their fully-vaccinated status under this policy by obtaining, if applicable, any FDA-approved boosters.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.

Please visit our career page at: http://www.guardanthealth.com/jobs/



Share |
Contact Information
Contact Name:
Company Name: Guardant Health
Company Description:

Please visit our employer showcase!
Apply Now | Forward Job to a Friend | More Jobs From This Employer

(Advertise Here)
Who's Online
>> more | invite 
Latest Photos
>> more | add
Most Popular Bloggers
tanisha grant has logged 26556 blog subscribers!
composer creator has logged 18573 blog subscribers!
>> more | add 
Latest Member Activity
nora herrera just edited her profile. 02:56PM
nora herrera just became a new member. 02:27PM
krystal bostick just became a new member. 02:27PM
jadora james just edited her profile. 09:05PM
charlie hardy just edited his profile. 02:33PM
charlie hardy just became a new member. 02:30PM
yaa astar just became a new member. 02:13PM
toluwanimi ijarotimi just became a new member. 04:01AM
michael braco just became a new member. 06:36AM
melonna clarke just became a new member. 02:16PM
cornelius davis just became a new member. 09:07PM
john munoz just became a new member. 11:35AM
>> more | invite friends